Continuous Evolution Profiles for Electronic-Tongue-Based Analysis†

1. Dr. Yanxia Hou^1,*, 
2. Maria Genua¹, 
3. Dr. Dayane Tada Batista¹, 
4. Dr. Roberto Calemczuk¹, 
5. Dr. Arnaud Buhot¹, 
6. Pauline Fornarelli², 
7. Dr. Jamal Koubachi², 
8. Prof. David Bonnaffé^2,*, 
9. Els Saesen³, 
10. Dr. Cédric Laguri³, 
11. Dr. Hugues Lortat-Jacob³, 
12. Dr. Thierry Livache^1,*

Article first published online: 11 SEP 2012

Licking the problem: A new type of electronic tongue was constructed by self-assembly on the surface of a surface plasmon resonance (SPR) imaging prism with combinations of simple building blocks. The resulting combinatorial array was used to detect proteins in solution (see scheme) using SPR imaging to monitor the interactions. The signal from each spot was dependent on its composition and the protein infused, and correlated with the response of its neighbors.